The association of personality trait on treatment outcomes in patients with chronic prostatitis/chronic pelvic pain syndrome: An exploratory study☆
Introduction
An increasing amount of evidence clearly suggests that the personality profile of an individual is involved in the development of, and the treatment response to, various neuropsychiatric disorders [1], [2], [3]. In this context, a recent study found that the psychometric profiles of patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) exhibited significantly higher scores on all assessments, except type-A behavior, relative to healthy controls [4], [5].
According to the first unselected population-based study to explore personality features in patients with prostatitis syndromes [6], patients with prostatitis were significantly more occupied, nervous, and meticulous than controls. Likewise, several studies, although limited and incomplete, have proposed that personality may be involved in the susceptibility of an individual to prostatitis and/or related disorders [7], [8], [9], [10], [11], [12]. The trait nature of one's personality profile is supported by findings from a 2-year observation of illness behavior and personality changes in a small sample of patients with CP, which found that the subjective well-being (psychosocial and somatic aspects) of patients was impaired, but the personality of patients did not change [13].
The recent turn towards a novel understanding of CP/CPPS as a heterogenous syndrome rather than a homogeneous disease has led to the development of specific classification criteria and treatment strategies based on individual patients' clinical characteristics [14], [15], [16], [17]. Almost half of the patients in one study were clinically heterogenous [18]. Specific personality facets have also been found to be related to depression and treatment outcomes, and it has been proposed that screening for certain personality traits at the start of treatment might help to identify patients at risk for an inadequate response to treatment [2].
Thus, it has been hypothesized that personality traits may affect the severity of CP/CPPS, as well as the treatment outcomes of CP/CPPS patients, following routine treatment, because a person's personality profile is a crucial factor that can influence their response to given stressors and/or diseases, and may be a strong predictor of perceived health status and use of coping strategies [19], [20], [21]. However, there is a paucity of data regarding the role of personality traits in the treatment of CP/CPPS, particularly using a validated and brief personality scale and in an Asian population.
Section snippets
Study design
This study was a 12-week prospective observational study with routine treatment.
Patients
Male participants were recruited at an outpatient clinic treating prostatitis in the Department of Urology at Bucheon St. Mary's Hospital in Bucheon, Kyeonggi-Do, Korea between April 2011 and March 2012. The clinical diagnosis of CP/CPPS was based on an NIH consensus regarding CP/CPPS symptoms [22].
Few exclusion criteria were applied because our study was performed during routine practice. However, patients who were
Baseline characteristics
Of the 324 patients screened (reasons for exclusion: refusal to participate n = 218, pyuria with urinalysis/urine culture n = 15, BPH n = 9, prostatic cancer n = 2), 80 agreed to be enrolled in the study and 66 (82.5%) returned for the completion of all rating scales at the final visit. Descriptive data of the demographic and clinical characteristics of all participants are summarized and compared by personality traits (Table 1).
The mean age of the population ranged from 45 to 52 years and the majority
Discussion
Despite the fact that this study is preliminary, our findings suggest that personality traits may be associated with various clinical parameters at baseline, and affect the treatment response after 12 weeks of routine treatment. To our knowledge, this is the first study to assess the association of personality traits with treatment response based on a longitudinal follow-up in an Asian population.
One merit of this study is that the follow-up design made it possible to investigate the role of
Conflict of interest
None.
Acknowledgment
This study was funded by the Ministry of Health and Welfare, Korea (A120004).
References (66)
- et al.
Personality predicts recurrence of late-life depression
J Affect Disord
(2010) - et al.
Association of five-factor model personality domains and facets with presence, onset, and treatment outcomes of major depression in older adults
Am J Geriatr Psychiatry
(2013) - et al.
Psychometric profiles and hypothalamic–pituitary–adrenal axis function in men with chronic prostatitis/chronic pelvic pain syndrome
J Urol
(2008) - et al.
Stress induced hypothalamus–pituitary–adrenal axis responses and disturbances in psychological profiles in men with chronic prostatitis/chronic pelvic pain syndrome
J Urol
(2009) - et al.
Personality variables involved in chronic prostatitis
Urology
(1993) - et al.
Phenotypically directed multimodal therapy for chronic prostatitis/chronic pelvic pain syndrome: a prospective study using UPOINT
Urology
(2010) - et al.
Clinical phenotyping of patients with chronic prostatitis/chronic pelvic pain syndrome and correlation with symptom severity
Urology
(2009) - et al.
Is coping well a matter of personality? A study of euthymic unipolar and bipolar patients
J Affect Disord
(2013) - et al.
Overview summary statement. Diagnosis and management of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS)
Urology
(2002) - et al.
Validation of the Patient Health Questionnaire-9 Korean version in the elderly population: the Ansan Geriatric study
Compr Psychiatry
(2008)
Psychometric properties of the Patient Health Questionnaire-15 (PHQ-15) for measuring the somatic symptoms of psychiatric outpatients
Psychosomatics
Terazosin therapy for chronic prostatitis/chronic pelvic pain syndrome: a randomized, placebo controlled trial
J Urol
Interactions between life stressors and susceptibility genes (5-HTTLPR and BDNF) on depression in Korean elders
Biol Psychiatry
The association between bodily anxiety symptom dimensions and the scales of the Revised NEO Personality Inventory and the Temperament and Character Inventory
Compr Psychiatry
Coping style, personality and adolescent adjustment 10 years post-burn
Burns
Catastrophizing and pain-contingent rest predict patient adjustment in men with chronic prostatitis/chronic pelvic pain syndrome
J Pain
Management of chronic prostatitis/chronic pelvic pain syndrome: an evidence-based approach
Urology
Correction for multiple testing: is there a resolution?
Chest
Influences of personality traits on quality of life after stroke
Eur Neurol
Fears, sexual disturbances and personality features in men with prostatitis: a population-based cross-sectional study in Finland
BJU Int
An epidemiological study of patients with chronic prostatitis
BJU Int
Personality pathology underlying chronic prostatitis
Psychother Psychosom
Psychic disturbances in patients with chronic prostatis
Ann Clin Res
Psychological problems in chronic prostatitis patients with pain
Clin J Pain
Psychological problems in young men with chronic prostatitis-like symptoms
Scand J Urol Nephrol
Illness behavior and personality changes in patients with chronic prostatitis during a two-year follow-up period
Eur Urol
The role of phenotyping in chronic prostatitis/chronic pelvic pain syndrome
Curr Urol Rep
Phenotypic approach to the management of the chronic prostatitis/chronic pelvic pain syndrome
BJU Int
Classification and treatment of men with chronic prostatitis/chronic pelvic pain syndrome using the UPOINT system
World J Urol
Specific personality traits and coping styles predict affective symptoms in early post acute coronary syndrome inpatients
Int J Psychiatry Med
Personality pathology as a risk factor for negative health perception
J Pers Disord
NIH consensus definition and classification of prostatitis
JAMA
Management of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS): the studies, the evidence, and the impact
World J Urol
Cited by (30)
Dynamic Associations Between Daily Pain and Mood during Chemotherapy for Gynecologic Cancers
2024, Pain Management NursingWhy do newly diagnosed breast cancer patients seek a second opinion? – Second opinion seeking and its association with the physician-patient relationship
2019, Patient Education and CounselingCitation Excerpt :As an inadequate communication style by the physician and unsatisfied patient information needs correlate with increased fear and greater depression [7,14,15], we included fear of progression as a PRO by which to assess a possible relationship to the outcome of the SO and its possible influence on this decision-making process of seeking an SO. Finally, personality was included as it associates with several health outcomes such as symptom manifestation, illness severity or treatment outcomes [16–19] and because neurotic individuals in particular tend to experience more negative emotions such as anxiety, worry or self-consciousness [20]. Therefore, we also wanted to assess whether personality traits influence the decision to seek an SO.
Predictors of pain, urinary symptoms and quality of life in patients with chronic pelvic pain syndrome (CPPS): A prospective 12-month follow-up study
2018, Journal of Psychosomatic ResearchCitation Excerpt :However, adjustment for other potential psychosocial confounders was not performed. Koh et al. found that neuroticism was associated with a significantly poorer treatment response and higher levels of depression and somatization in patients with CP/CPPS after 12 weeks [36], and stress predicted pain intensity and disability in patients with CP/CPPS after 6 months [37]. In women with endometriosis, catastrophizing was associated with a decreased probability of pain improvement after one year [38].
Factors Affecting Quality of Life at Different Intervals After Treatment of Localized Prostate Cancer: Unique Influence of Treatment Decision Making Satisfaction, Personality and Sexual Functioning
2016, Journal of UrologyCitation Excerpt :The current study is one of the first to examine the role of neuroticism and its association with QOL after treatment for prostate cancer. Research in other clinical populations has repeatedly shown that individuals with higher levels of neuroticism report lower QOL,10–12 show greater reluctance toward health care, report decreased ability to cope with cancer related stressors30 and have increased mortality rates.13,15–18 Of interest, the relationship between prostate cancer anxiety, fear of recurrence and QOL lost significance after the 1 to 3-year posttreatment mark while neuroticism remained significantly associated with QOL into the greater than 3 to 5-year posttreatment time point.
Subgroups of patients with fibromyalgia according to Gray's personality model: Study on psychological characteristics
2015, Revista Colombiana de Reumatologia
- ☆
The English in this document has been checked by at least two professional editors, both native speakers of English. For a certificate, please see: http://www.textcheck.com/certificate/ne3ziv.