Journal of Psychosomatic Research
Volume 69, Issue 3 , Pages 237-239 , September 2010

Heart-focused anxiety as a mediating variable in the treatment of non-cardiac chest pain by cognitive-behavioural and psychopharmacological treatment by paroxetine

  • Olafur S. Palsson

      Affiliations

    • Corresponding Author InformationCenter for Functional GI & Motility Disorders, Campus Box 7080, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7080, USA.

Received 27 April 2010 ,Revised 27 April 2010 ,Accepted 27 April 2010.

References 

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  2. Eslick GD. Non-cardiac chest pain: epidemiology, natural history, health care seeking behaviour and quality of life. Gastroenterol Clin North Am. 2005;33:1–23
  3. Pope JH, Ruthazer R, Beshansky JR, Griffith JL, Selker HP. Clinical features of emergency department patients presenting with symptoms suggestive of acute cardiac ischemia: a multicenter study. J Thromb Thrombolysis. 1998;6:63–74
  4. Eslick GD, Coulshed DS, Talley NJ. Diagnosis and treatment of noncardiac chest pain. Nat Clin Pract Gastroenterol Hepatol. 2005;2:463–472
  5. Hewson EG, Sinclair JW, Dalton CB, Richter JE. Twenty-four-hour esophageal pH monitoring: the most useful test for evaluating noncardiac chest pain. Am J Med. 1991;90:576–583
  6. Van HD, Fass R. The pathophysiology of non-cardiac chest pain. J Gastroenterol Hepatol. 2005;(20 Suppl):S6–S13
  7. Cremonini F, Wise J, Moayyedi P, Talley NJ. Diagnostic and therapeutic use of proton pump inhibitors in non-cardiac chest pain: a metaanalysis. Am J Gastroenterol. 2005;100:1226–1232
  8. Eslick GD, Talley NJ. Natural history and predictors of outcome for non-cardiac chest pain: a prospective 4-year cohort study. Neurogastroenterol Motil. 2008;20:989–997
  9. Potts SG, Bass CM. Psychosocial outcome and use of medical resources in patients with chest pain and normal or near-normal coronary arteries: a long-term follow-up study. Q J Med. 1993;86:583–593
  10. Eslick GD, Talley NJ. Non-cardiac chest pain: predictors of health care seeking, the types of health care professional consulted, work absenteeism and interruption of daily activities. Aliment Pharmacol Ther. 2004;20:909–915
  11. Eslick GD, Coulshed DS, Talley NJ. Review article: the burden of illness of non-cardiac chest pain. Aliment Pharmacol Ther. 2002;16:1217–1223
  12. Kisely SR, Campbell LA, Skerritt P, Yelland MJ. Psychological interventions for symptomatic management of non-specific chest pain in patients with normal coronary anatomy. Cochrane Database Syst Rev. 2010;CD004101
  13. Chahal PS, Rao SS. Functional chest pain: nociception and visceral hyperalgesia. J Clin Gastroenterol. 2005;39:S204–S209
  14. Eifert GH, Thompson RN, Zwolenski MJ, Edwards K, Frazer NL, Haddad JW, et al. The Cardiac Anxiety Questionnaire: development and preliminary validity. Behav Res Ther. 2010;38:1039–1053
  15. Kraemer HC, Wilson GT, Fairburn CG, Agras WS. Mediators and moderators of treatment effects in randomized clinical trials. Arch Gen Psychiatry. 2002;59:877–883
  16. White KS, Craft JM, Gervino EV. Anxiety and hypervigilance to cardiopulmonary sensations in non-cardiac chest pain patients with and without psychiatric disorders. Behav Res Ther. 2010;

PII: S0022-3999(10)00213-8

doi: 10.1016/j.jpsychores.2010.04.016

Journal of Psychosomatic Research
Volume 69, Issue 3 , Pages 237-239 , September 2010

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