Journal of Psychosomatic Research
Volume 58, Issue 2 , Pages 173-178 , February 2005

Biopsychosocial predictors of fatigue in chronic hepatitis C

  • Robin C. Hilsabeck

      Affiliations

    • Department of Neuropsychiatry and Behavioral Science, Texas Tech University Health Sciences Center, 3601 4th Street, STOP 8321, Lubbock, TX 79430, United States
    • Division of Gastroenterology, Department of Medicine, University of California, San Diego, CA, United States
    • Department of Psychiatry, University of California, San Diego, CA, United States
    • Corresponding Author InformationCorresponding author. Department of Neuropsychiatry and Behavioral Science, Texas Tech University Health Sciences Center, 3601 4th Street, STOP 8321, Lubbock, TX 79430, United States. Tel.: +1 806 743 4999x289; fax: +1 806 743 1147
  • ,
  • Tarek I. Hassanein

      Affiliations

    • Division of Gastroenterology, Department of Medicine, University of California, San Diego, CA, United States
  • ,
  • William Perry

      Affiliations

    • Department of Psychiatry, University of California, San Diego, CA, United States

Received 28 May 2003 ,Accepted 7 July 2004.

References 

  1. Schiff ER. Hepatitis C today: the standard of care. Treat Report Gastroenterol. 2000;1–4(July 7)
  2. Wong JB, McQuillan GM, McHutchinson JG, Poynard T. Estimating future hepatitis C morbidity, mortality, and costs in the United States. Am J Public Health. 2000;90:1562–1569
  3. Lee DH, Jamal H, Regenstein FG, Perrillo RP. Morbidity of chronic hepatitis C as seen in a tertiary care medical center. Dig Dis Sci. 1997;42:186–191
  4. Kenny-Walsh E. Clinical outcomes after hepatitis C infection from contaminated anti-D immune globulin. N Engl J Med. 1999;340:1228–1233
  5. Barkuizen A, Rosen HR, Wolf S, Flora K, Benner K, Bennett RM. Musculoskeletal pain and fatigue are associated with chronic hepatitis C. Am J Gastroenterol. 1999;94:1355–1360
  6. Goh J, Coughlan B, Quinn J, O'Keane C, Crowe J. Fatigue does not correlate with the degree of hepatitis or the presence of autoimmune disorders in chronic hepatitis C infection. Eur J Gastroenterol Hepatol. 1999;11:833–838
  7. Davis GL, Balart LA, Schiff ER, Lindsay K, Bodenheimer HC, Perrillo RP, et al. Assessing health-related quality of life in chronic hepatitis C using the Sickness Impact Profile. Clin Ther. 1994;16:334–343
  8. Jones EA. Relief from profound fatigue associated with chronic liver disease by long-term ondansetron therapy. Lancet. 1999;354:397
  9. Dwight MM, Kowdley KV, Russo JE, Ciechanowski PS, Larson AM, Katon WJ. Depression, fatigue, and functional disability in patients with chronic hepatitis C. J Psychsom Res. 2000;49:311–317
  10. Khakoo S, Glue P, Grellier L, Wells B, Dash C, Murray-Lyon I, et al. Ribavirin and interferon alfa-2b in chronic hepatitis C: assessment of possible pharmacokinetic and pharmacodynamic interactions. Br J Clin Pharmacol. 1998;46:563–570
  11. Woo MH, Burnakis TG. Interferon alfa in the treatment of chronic vial hepatitis B and C. Ann Pharmacother. 1997;31:330–337
  12. Cotler SJ, Wartelle CF, Larson AM, Gretch DR, Jensen DM, Carithers RL. Pretreatment symptoms and dosing regimen predict side-effects of interferon therapy for hepatitis C. J Viral Hepat. 2000;7:211–217
  13. Yamada M, Fukuda Y, Koyama Y, Nakano I, Urano F, Isobe K, et al. A long-term follow-up study of interferon treatment for chronic hepatitis C in Japanese patients with congenital bleeding disorders. Eur J Haematol. 1996;57:165–170
  14. McDonald J, Jayasuriya R, Bindley P, Gonsalvez C, Gluseska S. Fatigue and psychological disorders in chronic hepatitis C. J Gastroenterol Hepatol. 2002;17:171–176
  15. Gershon AS, Margulies M, Gorczynski RM, Heathcote EJ. Serum cytokine values and fatigue in chronic hepatitis C infection. J Viral Hepat. 2000;7:397–402
  16. Hassoun Z, Willems B, Deslauriers J, Nguyen BN, Huet P. Assessment of fatigue in patients with chronic hepatitis C using the Fatigue Impact Scale. Dig Dis Sci. 2002;47:2674–2681
  17. Verbrugge LM. Sex differences in complaints and diagnoses. J Behav Med. 1980;3:327–355
  18. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 4th ed. Washington DC: American Psychiatric Association; 1994;
  19. Desmorat H. Quality of life during chronic hepatitis C: study of 466 patients before treatment. Hepatology. 1998;28:472A
  20. Kiecolt-Glaser JK, Glaser R. Psychoneuroimmunology and health consequences: data and shared mechanisms. Psychosom Med. 1995;57:269–274
  21. Cohen S, Doyle WJ, Skoner DP, Rabin BS, Gwaltney JM. Social ties and susceptibility to the common cold. J Am Med Assoc. 1997;277:1940–1944
  22. House JS, Landis KR, Umberson D. Social relationships and health. Science. 1988;241:540–545
  23. Fawzy FI, Fawzy NW, Hyun CS, Gutherie D, Fahey JL, Morton D. Malignant melanoma: effects of an early structured psychiatric intervention, coping, and affective state on recurrence and survival six years later. Arch Gen Psychiatry. 1993;50:681–689
  24. Linden W, Stossel C, Maurice J. Psychosocial interventions for patients with coronary artery disease. Arch Intern Med. 1996;156:745–752
  25. Funch DP, Mettlin C. The role of support in relation to recovery from breast cancer. Soc Sci Med. 1982;16:91–98
  26. Bultmann U, Kant IJ, Van Den Brandt PA, Kasl SV. Psychosocial work characteristics as risk factors for the onset of fatigue and psychological distress: prospective results from the Maastrict Cohort Study. Psychol Med. 2002;32:333–345
  27. The French METAVIR Cooperative Study Group . Interobserver and intraobserver variation in liver biopsy interpretation in patients with chronic hepatitis C. Hepatology. 1994;20:15–20
  28. Pugh RH, Murray-Lysh IM, Dawson JL, Williams R. Transection of the oesophagus for bleeding esophageal varieces. Br J Surg. 1973;60:646–649
  29. Piper B, Lindsey A, Dodd M, Ferketich S, Paul S, Weller S. The development of an instrument to measure the subjective dimension of fatigue. In:  Funk S,  Tomquist E,  Champagne M,  Wiesc R editor. Key aspects of comfort: management of pain, fatigue, and nausea. New York: Springer; 1989;p. 199–208
  30. Belza BL, Henke CJ, Yelin EH, Epstein WV, Gilliss CL. Correlates of fatigue in older adults with rheumatoid arthritis. Nurs Res. 1993;42:93–99
  31. Belza BL. Comparison of self-reported fatigue in rheumatoid arthritis and controls. J Rheumatol. 1995;22:639–643
  32. Winstead-Fry P. Psychometric assessment of four fatigue scales with a sample of rural cancer patients. J Nurs Meas. 1998;6:111–121
  33. Beck AT, Steer RA, Brown GK. Beck depression inventory—second edition: manual. San Antonio (TX): Psychological Corporation; 1996;
  34. Singh N, Gayowski T, Wagener MM, Marino IR. Vulnerability to psychologic distress and depression in patients with end-stage liver disease due to hepatitis C virus. Clin Transplant. 1997;11:406–411
  35. Ware JE, Sherbourne CD. The MOS 36-item short-form health survey (SF-36): I. Conceptual framework and item selection. Med Care. 1992;30:473–483
  36. McHorney CA, Ware JE, Raczek AE. The MOS 36-item short-form health status survey (SF-36): II. Psychometric and clinical tests of validity in measuring physical and mental health constructs. Med Care. 1993;31:247–263
  37. McHorney CA, Ware JE, Lu JFR, Sherbourne CD. The MOS 36-item Short-form Health Survey (SF-36): III. Tests of data quality, scaling assumptions and reliability across diverse patient groups. Med Care. 1994;3240–3266
  38. Katz JN, Larson MG, Phillips CB, Fossel AH, Liang MH. Comparative measurement sensitivity of short and longer health status instruments. Med Care. 1992;30:917–925
  39. Foster GR, Goldin RD, Thomas HC. Chronic hepatitis C virus infection causes a significant reduction in quality of life in the absence of cirrhosis. Hepatology. 1998;27:209–212
  40. Bonkovsky HL, Woolley JM, The Consensus Interferon Study Group . Reduction of health-related quality of life in chronic hepatitis C and improvement with interferon therapy. Hepatology. 1999;29:264–270
  41. Dunkel-Schetter C. Social support in cancer: findings based on patient interviews and their implications. J Soc Issues. 1984;40:77–98
  42. Zemore R, Shepel L. Effects of breast cancer and mastectomy on emotional support and adjustment. Soc Sci Med. 1989;28:19–27
  43. Heitzmann CA, Kaplan RM. Interaction between sex and social support in the control of type II diabetes mellitus. J Consult Clin Psychol. 1984;52:1087–1089
  44. Primomo J, Yates BC, Woods NF. Social support for women during chronic illness: the relationship among sources and types of adjustment. Res Nurs Health. 1990;13:153–161
  45. Rose M, Burkert U, Scholler G, Schirop T, Danzer G, Klapp BF. Determinants of the quality of life of patients with diabetes under intensified insulin therapy. Diabetes Care. 1998;21:1876–1885
  46. Umberson D. Family status and health behaviors: social control as a dimension of social integration. J Health Soc Behav. 1987;28:306–319
  47. Uchino BN, Uno D, Holt-Lunstad J. Social support, physiological processes, and health. Curr Dir Psychol Sci. 1999;8:145–148
  48. Ciechanowski PS, Katon WJ, Russ JE, Dwight-Johnson MM. Association of attachment style to lifetime medically unexplained symptoms in patients with hepatitis C. Psychosomatics. 2002;43:206–212
  49. Fontana RJ, Hussain KB, Schwartz SM, Moyer CA, Su GL, Lok ASF. Emotional distress in chronic hepatitis C patients not receiving antiviral therapy. J Hepatol. 2002;36:401–407
  50. Piche T, Gelsi E, Schneider SM, Hébuterne X, Giudicelli J, Ferrua B, et al. Fatigue is associated with high circulating leptin levels in chronic hepatitis C. Gut. 2002;51:434–439
  51. Spiegel D, Bloom JR, Kraemer HC, Gottheil E. Effect of psychosocial treatment on survival of patients with metastatic breast cancer. Lancet. 1989;334:888–891

PII: S0022-3999(04)00517-3

doi: 10.1016/j.jpsychores.2004.07.003

Journal of Psychosomatic Research
Volume 58, Issue 2 , Pages 173-178 , February 2005