Journal of Psychosomatic Research
Volume 57, Issue 4 , Pages 391-398 , October 2004

The effect of brief exercise cessation on pain, fatigue, and mood symptom development in healthy, fit individuals

  • Jennifer M. Glass

      Affiliations

    • Department of Psychiatry and Institute for Social Research, University of Michigan, Ann Arbor, MI, USA
    • Corresponding Author InformationCorresponding author. Institute for Social Research, University of Michigan, Room 5256, 426 Thompson Street, Ann Arbor, MI 48106-1248, USA. Tel.: +1-734-763-1512; fax: +1-734-764-3576
    • ,
  • Angela K. Lyden

      Affiliations

    • Division of Rheumatology, Department of Medicine, University of Michigan, Ann Arbor, MI, USA
    • ,
  • Frank Petzke

      Affiliations

    • Department of Anesthesiology, University of Cologne, Cologne, Germany
    • ,
  • Phyllis Stein

      Affiliations

    • Cardiovascular Division, Washington University, St. Louis, MO, USA
    • ,
  • Gail Whalen

      Affiliations

    • Division of Rheumatology, Immunology, and Allergy, Georgetown University, Washington, DC, USA
    • ,
  • Kirsten Ambrose

      Affiliations

    • Division of Rheumatology, Department of Medicine, University of Michigan, Ann Arbor, MI, USA
    • ,
  • George Chrousos

      Affiliations

    • National Institute for Child Health & Development, NIH, Bethesda, MD, USA
    • ,
  • Daniel J. Clauw

      Affiliations

    • Division of Rheumatology, Department of Medicine, University of Michigan, Ann Arbor, MI, USA

References 

  1. Yunus MB, Holt GS, Masi AT, Aldag JC. Fibromyalgia syndrome among the elderly. Comparison with younger patients. J Am Geriatr Soc. 1988;36(11):987–995
  2. Turner R, Le Bihan D, Moonen CTW, Frank J. Echo-planar imaging of deoxygenation episodes in cat brain at 2T;. 1991;
  3. Crofford LJ, Demitrack MA. Evidence that abnormalities of central neurohormonal systems are key to understanding fibromyalgia and chronic fatigue syndrome. Rheum Dis Clin North Am. 1996;22(2):267–284
  4. Nisenbaum R, Reyes M, Mawle AC, Reeves WC. Factor analysis of unexplained severe fatigue and interrelated symptoms: overlap with criteria for chronic fatigue syndrome. Am J Epidemiol 7-1-. 1998;148(1):72–77
  5. King SJ, Wessel J, Bhambhani Y, Sholter D, Maksymowych W. Predictors of success of intervention programs for persons with fibromyalgia. J Rheumatol. 2002;29(5):1034–1040
  6. Buxton J, White M, Osoba D. Patients' experiences using a computerized program with a touch-sensitive video monitor for the assessment of health-related quality of life. Qual Life Res. 1998;7(6):513–519
  7. Fields HL. Core curriculum for professional education in pain. Seattle: IASP Publications; 1991;
  8. Buskila D, Neumann L, Vaisberg G, Alkalay D, Wolfe F. Increased rates of fibromyalgia following cervical spine injury. A controlled study of 161 cases of traumatic injury. Arthritis Rheum. 1997;40(3):446–452
  9. Waylonis GW, Perkins RH. Post-traumatic fibromyalgia. A long-term follow-up. Am J Phys Med Rehabil. 1994;73(6):403–412
  10. Goldenberg DL. Fibromyalgia and its relation to chronic fatigue syndrome, viral illness and immune abnormalities. J Rheumatol Suppl. 1989;19:91–93
  11. Culclasure TF, Enzenauer RJ, West SG. Post-traumatic stress disorder presenting as fibromyalgia. Am J Med. 1993;94:548–549 May 1993
  12. Hazlett RL, Haynes SN. Fibromyalgia: a time-series analysis of the stressor-physical symptom association. J Behav Med. 1993;15:541–558 December 1992
  13. Dailey PA, Bishop GD, Russell IJ, Fletcher EM. Psychological stress and the fibrositis/fibromyalgia syndrome. J Rheumatol. 1993;17:1380–1385 October 1990
  14. Demitrack MA, Dale JK, Straus SE, Laue L, Listwak SJ, Kruesi MJ, et al. Evidence for impaired activation of the hypothalamic–pituitary–adrenal axis in patients with chronic fatigue syndrome. J Clin Endocrinol Metab. 1994;73:1224–1234 December 1991
  15. Demitrack MA, Dale JK, Straus SE, Laue L, Listwak SJ, Kruesi MJ, et al. Evidence for impaired activation of the hypothalamic–pituitary–adrenal axis in patients with chronic fatigue syndrome. J Clin Endocrinol Metab. 1991;73(6):1224–1234
  16. Crofford LJ, Engleberg NC, Demitrack MA. Neurohormonal perturbations in fibromyalgia. Bailliere's Clin Rheumatol. 1996;10(2):365–378
  17. Samborski W, Stratz T, Kretzmann WM, Mennet P, Muller W. Comparative studies of the incidence of vegetative and functional disorders in backache and generalized tendomyopathies. Z Rheumatol. 1991;50(6):378–381
  18. Crofford LJ, Pillemer SR, Kalogeras KT, Cash JM, Michelson D, Kling MA, et al. Hypothalamic–pituitary–adrenal axis perturbations in patients with fibromyalgia. Arthritis Rheum. 1994;37(11):1583–1592
  19. Gracely RH, Petzke F, Wolf JM, Clauw DJ. Functional magnetic resonance imaging evidence of augmented pain processing in fibromyalgia. Arthritis Rheum. 2002;46(5):1333–1343
  20. Yunus MB. Towards a model of pathophysiology of fibromyalgia: aberrant central pain mechanisms with peripheral modulation. editorial J Rheumatol. 1992;19(6):846–850
  21. Busch A, Schachter CL, Peloso PM, Bombardier C. Exercise for treating fibromyalgia syndrome. Cochrane Database Syst Rev. 2002;(3):CD003786.
  22. Goudsmit EM. Measuring the quality of trials of treatments for chronic fatigue syndrome. JAMA. 2001;286(24):3078–3079 December 26
  23. Guieu R, Blin O, Pouget J, Serratrice G. Nociceptive threshold and physical activity. Can J Neurol Sci. 1992;19(1):69–71
  24. Janal MN, Colt EW, Clark WC, Glusman M. Pain sensitivity, mood and plasma endocrine levels in man following long-distance running: effects of naloxone. Pain. 1984;19(1):13–25
  25. Mondin GW, Morgan WP, Piering PN, Stegner AJ, Stotesbery CL, Trine MR, et al. Psychological consequences of exercise deprivation in habitual exercisers. Med Sci Sports Exerc. 1996;28(9):1199–1203
  26. Luger A, Deuster PA, Kyle SB, Gallucci WT, Montgomery LC, Gold PW, et al. Acute hypothalamic–pitutitary–adrenal response to the stress of treadmill exercise: physiological adaptations to physical training. N Engl J Med. 1987;316(21):1309–1315
  27. Petrides JS, Mueller GP, Chrousos G, Kalogeras K, Deuster PA. Exercise-induced activation of the hypothalamic–pituitary–adrenal (HPA) axis: differential sensitivity to glucocorticoid suppression. J Clin Endocrinol Metab. 1994;79:377–383
  28. Granges G, Littlejohn GO. A comparative study of clinical signs in fibromyalgia/fibrositis syndrome, healthy and exercising subjects. J Rheumatol. 1993;20:344–351 February 1993
  29. Melzack R. The short-form McGill pain questionnaire. Pain. 1987;30(2):191–197
  30. Smets EM, Garssen B, Bonke B, De Haes JC. The Multidimensional Fatigue Inventory (MFI) psychometric qualities of an instrument to assess fatigue. J Psychosom Res. 1995;39(3):315–325
  31. Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J. An inventory for measuring depression. Arch Gen Psychiatry. 1961;4:53–63 June
  32. Palo Alto, CA Consulting Psychologists, 1983; 1996.
  33. Wolfe F, Smythe HA, Yunus MB, Bennett RM, Bombardier C, Goldenberg DL, et al. The American College of Rheumatology 1990 criteria for the classification of fibromyalgia. Report of the multicenter criteria committee. see comments Arthritis Rheum. 1993;33:160–172 February 1990
  34. Sorensen J, Graven-Nielsen T, Henriksson KG, Bengtsson M, Arendt-Nielsen L. Hyperexcitability in fibromyalgia. J Rheumatol. 1998;25:152–155
  35. Radulovic D, Barbey JT, Katz P, Baraniuk J, Clauw DJ. Tilt table testing as a measure of dysautonomia in fibromyalgia (FM). Arthritis Rheum. 1995;38(6):R25
  36. Soetekouw PM, Lenders JW, Bleijenberg G, Thien T, van der Meer JW. Autonomic function in patients with chronic fatigue syndrome. Clin Auton Res. 1999;9(6):334–340
  37. Clauw DJ, Heshmat Y, Groner K, Gondy G, Barbey JT. Heart rate variability as a measure of autonomic function in patients with fibromyalgia. Arthritis Rheum. 1996;39(Suppl 9):S276
  38. Clauw DJ, Radulovic D, Heshmat Y, Barbey JT. Heart rate variability as a measure of autonomic function in patients with fibromyalgia (FM) and chronic fatigue syndrome (CFS). Arthritis Rheum. 1995;38(Suppl 6):R25
  39. Cohen H, Neumann L, Shore M, Amir M, Cassuto Y, Buskila D. Autonomic dysfunction in patients with fibromyalgia: application of power spectral analysis of heart rate variability. see comments Semin Arthritis Rheum. 2000;29(4):217–227
  40. Gr:onblad M, Nykanen J, Konttinen Y, Jarvinen E, Helve T. Effect of zopiclone on sleep quality, morning stiffness, widespread tenderness and pain and general discomfort in primary fibromyalgia patients. A double-blind randomized trial. Clin Rheumatol. 1993;12:186–191 June 1993
  41. Barsky AJ, Goodson JD, Lane RS, Cleary PD. The amplification of somatic symptoms. Psychosom Med. 1988;50(5):510–519
  42. Akselrod S, Gordon D, Ubel FA, Shannon DC, Barger AC, Cohen RJ. Power spectrum analysis of heart rate fluctuation: a quantitative probe of beat-to-beat cardiovascular control. Science. 1981;213:220–222
  43. Schedlowski M, Jacobs R, Stratmann G, Richter S, Hadicke A, Tewes U, et al. Changes of natural killer cells during acute psychological stress. J Clin Immunol. 1993;13(2):119–126
  44. Tonnesen E, Christensen NJ, Brinklov MM. Natural killer cell activity during cortisol and adrenaline infusion in healthy volunteers. Eur J Clin Invest. 1987;17:497–503
  45. Chrousos GP. The hypothalamic–pituitary–adrenal axis and immune-mediated inflammation. N Engl J Med. 1995;332(20):1351–1362 May 18
  46. Whiteside TL, Friberg D. Natural killer cells and natural killer cell activity in chronic fatigue syndrome. Am J Med. 1998;105(3A):27S–34S September 28
  47. Bates DW, Buchwald D, Lee J, Kith P, Doolittle T, Rutherford C, et al. Clinical laboratory test findings in patients with chronic fatigue syndrome. Arch Intern Med. 1995;155(1):97–103 January 9
  48. Buchwald D, Wener MH, Pearlman T, Kith P. Markers of inflammation and immune activation in chronic fatigue and chronic fatigue syndrome. J Rheumatol. 1997;24(2):372–376
  49. Klimas NG, Salvato FR, Morgan R, Fletcher MA. Immunologic abnormalities in chronic fatigue syndrome. J Clin Microbiol. 1990;28(6):1403–1410
  50. Barker E, Fujimura SF, Fadem MB, Landay AL, Levy JA. Immunologic abnormalities associated with chronic fatigue syndrome. Clin Infect Dis. 1994;18(Suppl 1):S136–S141
  51. Buchwald D, Komaroff AL. Review of laboratory findings for patients with chronic fatigue syndrome. Rev Infect Dis. 1991;13(Suppl 1):S12–S18
  52. Bell IR, Baldwin CM, Schwartz GE. Illness from low levels of environmental chemicals: relevance to chronic fatigue syndrome and fibromyalgia. Am J Med. 1998;105(3A):74S–82S September 28
  53. Clauw DJ, Chrousos GP. Chronic pain and fatigue syndromes: overlapping clinical and neuroendocrine features and potential pathogenic mechanisms. Neuroimmunomodulation. 1997;4(3):134–153
  54. Clauw DJ, Whalen G, Groner K, Lyden A, Katz P, Cupps T. Is autonomic dysfunction the cause of “immune dysfunction” in fibromyalgia (FM) and Chronic Fatigue Syndrome (CFS)?. Arthritis Rheum. 1997;40(Suppl 9):S42
  55. Lekander M, Fredrikson M, Wik G. Neuroimmune relations in patients with fibromyalgia: a positron emission tomography study. Neurosci Lett. 2000;282(3):193–196 March 24
  56. Clauw DJ, Whalen G, Groner K, Lyden A, Katz P, Cupps T. Is autonomic dysfunction the cause of “immune dysfunction” in fibromyalgia (FM) and Chronic Fatigue Syndrome (CFS)?. Arthritis Rheum. 1997;40(Suppl 9):S42
  57. Cell Immunol, vol. 120, 1989.
  58. Demitrack MA. Chronic fatigue syndrome: a disease of the hypothalamic–pituitary–adrenal axis?. editorial Ann Med. 1994;26(1):1–5
  59. Catley D, Kaell AT, Kirschbaum C, Stone AA. A naturalistic evaluation of cortisol secretion in persons with fibromyalgia and rheumatoid arthritis. Arthritis Care Res. 2000;13(1):51–61
  60. Cofford LJ, Engleberg NC, Brucksch C, Eisner S, Papadopoulos E, Krstov M, et al. Analysis of circadian plasma ACTH and cortisol levels in patients with fibromyalgia (FM) and Chronic Fatigue Syndrome (CFS). Arthritis Rheum. 1996;39(Suppl 9):1487
  61. Coyle EF, Martin WH, Sinacore DR, Joyner MJ, Hagberg JM, Holloszy JO. Time course of loss of adaptations after stopping prolonged intense endurance training. J Appl Physiol. 1984;57(6):1857–1864
  62. Levine PH, Whiteside TL, Friberg D, Bryant J, Colclough G, Herberman RB. Dysfunction of natural killer activity in a family with chronic fatigue syndrome. Clin Immunol Immunopathol. 1998;88(1):96–104
  63. Martinez-Lavin M, Hermosillo AG. Autonomic nervous system dysfunction may explain the multisystem features of fibromyalgia. editorial; comment Semin Arthritis Rheum. 2000;29(4):197–199
  64. Crofford LJ, Demitrack MA. Evidence that abnormalities of central neurohormonal systems are key to understanding fibromyalgia and chronic fatigue syndrome. Rheum Dis Clin North Am. 1996;22(2):267–284
  65. Moldofsky H, Scarisbrick P. Induction of neurasthenic musculoskeletal pain syndrome by selective sleep stage deprivation. Psychosom Med. 1976;38:35–44

PII: S0022-3999(04)00080-7

doi: 10.1016/j.jpsychores.2004.04.002

Journal of Psychosomatic Research
Volume 57, Issue 4 , Pages 391-398 , October 2004

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