Journal of Psychosomatic Research
Volume 57, Issue 2 , Pages 189-194 , August 2004

Mild acute inflammatory stimulation induces transient negative mood

Received 29 April 2003 ,Accepted 5 August 2003.

References 

  1. Larson SJ, Dunn AJ. Behavioral effects of cytokines. Brain Behav Immun. 2001;15(4):371–387
  2. Konsman JP, Parnet P, Dantzer R. Cytokine-induced sickness behaviour: mechanisms and implications. Trends Neurosci. 2002;25(3):154–159
  3. Dantzer R. Cytokine-induced sickness behavior: where do we stand?. Brain Behav Immun. 2001;15(1):7–24
  4. Maes M, Capuron L, Ravaud A, Gualde N, Bosmans E, Egyed B, et al. Lowered serum dipeptidyl peptidase IV activity is associated with depressive symptoms and cytokine production in cancer patients receiving interleukin-2-based immunotherapy. Neuropsychopharmacology. 2001;24(2):130–140
  5. Spath-Schwalbe E, Hansen K, Schmidt F, Schrezenmeier H, Marshall L, Burger K, et al. Acute effects of recombinant human interleukin-6 on endocrine and central nervous sleep functions in healthy men. J Clin Endocrinol Metab. 1998;83(5):1573–1579
  6. Maes M. Major depression and activation of the inflammatory response system. Adv Exp Med Biol. 1999;461:25–46
  7. Kop WJ, Gottdiener JS, Tangen CM, Fried LP, McBurnie MA, Walston J, et al. Inflammation and coagulation factors in Persons >65 years of age with symptoms of depression but without evidence of myocardial ischemia. Am J Cardiol. 2002;89(4):419–424 15 Feb
  8. Steptoe A, Kunz-Ebrecht S, Owen N. Lack of association between depressive symptoms and markers of immune and vascular inflammation in middle-aged men and women. Psychol Med. 2003;33:667–674
  9. Wichers M, Maes M. The psychoneuroimmuno-pathophysiology of cytokine-induced depression in humans. Int J Neuropsychopharmacol. 2002;5(4):375–388
  10. Capuron L, Ravaud A, Dantzer R. Timing and specificity of the cognitive changes induced by interleukin-2 and interferon-alpha treatments in cancer patients. Psychosom Med. 2001;63(3):376–386
  11. Capuron L, Ravaud A, Gualde N, Bosmans E, Dantzer R, Maes M, et al. Association between immune activation and early depressive symptoms in cancer patients treated with interleukin-2-based therapy. Psychoneuroendocrinology. 2001;26(8):797–808
  12. Bonaccorso S, Marino V, Biondi M, Grimaldi F, Ippoliti F, Maes M. Depression induced by treatment with interferon-alpha in patients affected by hepatitis C virus. J Affect Disord. 2002;72(3):237–241
  13. Capuron L, Dantzer R. Cytokines and depression: the need for a new paradigm. Brain Behav Immun. 2003;17(1 Suppl):119–124
  14. Pollak Y, Yirmiya R. Cytokine-induced changes in mood and behaviour: implications for “depression due to a general medical condition”, immunotherapy and antidepressive treatment. Int J Neuropsychopharmacol. 2002;5(4):389–399
  15. Reichenberg A, Yirmiya R, Schuld A, Kraus T, Haack M, Morag A, et al. Cytokine-associated emotional and cognitive disturbances in humans. Arch Gen Psychiatry. 2001;58(5):445–452
  16. Hingorani AD, Cross J, Kharbanda RK, Mullen MJ, Bhagat K, Taylor M, et al. Acute systemic inflammation impairs endothelium-dependent dilatation in humans. Circulation. 2000;102(9):994–999 29 Aug
  17. Kharbanda RK, Walton B, Allen M, Klein N, Hingorani AD, MacAllister RJ, et al. Prevention of inflammation-induced endothelial dysfunction. A novel vasculo-protective action of aspirin. Circulation. 2002;105:2600–2604
  18. Ader R, Felten DL, Cohen N. Psychoneuroimmunology. 3rd ed. San Diego (CA): Academic Press; 2001;
  19. Maes M, Song C, Lin A, De Jongh R, Van Gastel A, Kenis G, et al. The effects of psychological stress on humans: increased production of pro-inflammatory cytokines and a Th1-like response in stress-induced anxiety. Cytokine. 1998;10(4):313–318
  20. Lutgendorf SK, Garand L, Buckwalter KC, Reimer TT, Hong SY, Lubaroff DM. Life stress, mood disturbance, and elevated interleukin-6 in healthy older women. J Gerontol A Biol Sci Med Sci. 1999;54(9):M434–M439
  21. Steptoe A, Owen N, Kunz-Ebrecht S, Mohamed-Ali V. Inflammatory cytokines, socioeconomic status, and acute stress responsivity. Brain Behav Immun. 2002;16(6):774–784
  22. De Gucht V, Fischler B, Demanet C. Immune dysfunction associated with chronic professional stress in nurses. Psychiatry Res. 1999;85(1):105–111 18 Jan
  23. Cohen S, Doyle WJ, Skoner DP. Psychological stress, cytokine production, and severity of upper respiratory illness. Psychosom Med. 1999;61(2):175–180
  24. Pearlin LI, Lieberman MA, Menaghan EG, Mullan JT. The stress process. J Health Soc Behav. 1981;22(4):337–356
  25. Ross CE, Huber J. Hardship and Depression. J Health Soc Behav. 1985;26(4):312–327
  26. Marmot MG, Smith GD, Stansfeld S, Patel C, North F, Head J, et al. Health inequalities among British Civil Servants: the Whitehall II study. Lancet. 1991;337(8754):1387–1393 8 Jun
  27. Bosma H, Marmot MG, Hemingway H, Nicholson AC, Brunner E, Stansfeld SA. Low job control and risk of coronary heart disease in Whitehall II (prospective cohort) study. BMJ. 1997;314(7080):558–565 22 Feb
  28. McNair DM, Lorr N, Droppleman LF. Manual for the profile of mood states. San Diego (CA): Education and Industrial Testing Service; 1981;
  29. Moses J, Steptoe A, Mathews A, Edwards S. The effects of exercise training on mental well-being in the normal population: a controlled trial. J Psychosom Res. 1989;33(1):47–61
  30. Morag M, Yirmiya R, Lerer B, Morag A. Influence of socioeconomic status on behavioral, emotional and cognitive effects of rubella vaccination: a prospective, double blind study. Psychoneuroendocrinology. 1998;23(4):337–351
  31. Kharbanda RK, Walton B, Allen M, Klein N, Hingorani AD, MacAllister RJ, et al. Prevention of inflammation-induced endothelial dysfunction: a novel vasculo-protective action of aspirin. Circulation. 2002;105(22):2600–2604 4 Jun
  32. Cohen S, Doyle WJ, Skoner DP, Rabin BS, Gwaltney JM. Social ties and susceptibility to the common cold. JAMA. 1997;277(24):1940–1944 25 Jun
  33. Cohen S, Tyrrell DA, Smith AP. Psychological stress and susceptibility to the common cold. N Engl J Med. 1991;325(9):606–612 29 Aug
  34. Ross R. Atherosclerosis—an inflammatory disease. N Engl J Med. 1999;340(2):115–126 14 Jan
  35. Libby P, Ridker PM, Maseri A. Inflammation and atherosclerosis. Circulation. 2002;105(9):1135–1143 5 Mar
  36. Biasucci LM, Liuzzo G, Fantuzzi G, Caligiuri G, Rebuzzi AG, Ginnetti F, et al. Increasing levels of interleukin (IL)-1Ra and IL-6 during the first 2 days of hospitalization in unstable angina are associated with increased risk of in-hospital coronary events. Circulation. 1999;99(16):2079–2084 27 Apr
  37. Ziegelstein RC. Depression in patients recovering from a myocardial infarction. JAMA. 2001;286(13):1621–1627 3 Oct
  38. Carney RM, Freedland KE, Miller GE, Jaffe AS. Depression as a risk factor for cardiac mortality and morbidity: a review of potential mechanisms. J Psychosom Res. 2002;53(4):897–902

PII: S0022-3999(03)00569-5

doi: 10.1016/S0022-3999(03)00569-5

Journal of Psychosomatic Research
Volume 57, Issue 2 , Pages 189-194 , August 2004