Journal of Psychosomatic Research
Volume 60, Issue 5 , Pages 461-467, May 2006

The Hospital Anxiety and Depression Scale depression subscale, but not the Beck Depression Inventory-Fast Scale, identifies patients with acute coronary syndrome at elevated risk of 1-year mortality

  • Frank Doyle

      Affiliations

    • Department of Psychology, Royal College of Surgeons in Ireland, 120 St Stephen's Green, Dublin 2, Ireland
    • Department of Epidemiology and Public Health Medicine, Royal College of Surgeons in Ireland, 120 St Stephen's Green, Dublin 2, Ireland
    • Corresponding Author InformationCorresponding author. Department of Epidemiology and Public Health Medicine, Royal College of Surgeons in Ireland, Dublin 2, Ireland. Tel.: +353 1 4022718; fax: +353 1 4022764.
  • ,
  • Hannah M. McGee

      Affiliations

    • Department of Psychology, Royal College of Surgeons in Ireland, 120 St Stephen's Green, Dublin 2, Ireland
  • ,
  • Davida De La Harpe

      Affiliations

    • Department of Epidemiology and Public Health Medicine, Royal College of Surgeons in Ireland, 120 St Stephen's Green, Dublin 2, Ireland
  • ,
  • Emer Shelley

      Affiliations

    • Department of Epidemiology and Public Health Medicine, Royal College of Surgeons in Ireland, 120 St Stephen's Green, Dublin 2, Ireland
  • ,
  • Ronán Conroy

      Affiliations

    • Department of Epidemiology and Public Health Medicine, Royal College of Surgeons in Ireland, 120 St Stephen's Green, Dublin 2, Ireland

Received 3 May 2005; received in revised form 16 August 2005; accepted 6 September 2005.

Abstract 

Objective

The objective of this study was to investigate the use of short-form depression scales in assessing 1-year mortality risk in a national sample of patients with acute coronary syndrome (ACS).

Methods

Patients with ACS (N=598) completed either the Hospital Anxiety and Depression Scale depression subscale (HADS-D) or the Beck Depression Inventory-Fast Scale (BDI-FS). Their mortality status was assessed at 1 year.

Results

Cox proportional hazards modeling showed that patients depressed at baseline (combining HADS-D and BDI-FS depressed cases) were more likely to die within 1 year [hazard ratio (HR)=2.8, 95% CI=1.4–5.7, P=.005], even when controlling for major medical and demographic variables (HR=4.1, 95% CI=1.6–10.3, P=.003). Scoring above the threshold on the HADS-D predicted mortality (HR=4.2, 95% CI=1.8–10.0, P=.001), but scoring above the threshold on the BDI-FS did not (HR=1.8, 95% CI=0.6–5.6, P=.291).

Conclusion

The HADS-D predicted increased risk of 1-year mortality in patients with ACS.

Keywords: Acute coronary syndrome, Acute myocardial infarction, Depressive disorder, Ireland, Mortality

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PII: S0022-3999(05)00391-0

doi:10.1016/j.jpsychores.2005.09.004

Journal of Psychosomatic Research
Volume 60, Issue 5 , Pages 461-467, May 2006